Satellite Glial Cell Markers

Cultured cells expressed glutamine synthetase glial fibrillary acidic protein and s100β suggesting they are satellite glial cells with a purity of 95.

Satellite glial cell markers.

After subculture cells were identified by immunofluorescence labeling for three satellite glial cell specific markers. The most specific markers of astrocytes are gfap and s100β. Ginhoux f and prinz m 2015 origin of microglia. Garden ga and campbell bm 2016 glial biomarkers in human central nervous system disease.

In a healthy nervous system astrocytes play essential roles in development regulation of blood flow by supporting endothelial cells in the blood brain barrier synaptic transmission and function and energy and metabolism by providing nutrients to neurons and synthesizing certain neurotransmitters. Sgcs may be identified by the expression of several glial markers such as glutamine synthetase gs and s100β. In the drgs the cell bodies of these primary afferents are anatomically surrounded by satellite glial cells sgcs forming distinct functional units. The p75ntr cells were also positive for the pan glial cell markers s100 nestin and sox10 but negative for fibroblast and macrophage markers.

From studies on rats and mice researchers have found that satellite glial cells express many neurotransmitter receptors such as muscarinic acetylcholine and erythropoietin receptors. Ginhoux f and prinz m 2015 origin of microglia. Here we developed the cellmarker databases aiming to provide a comprehensive and accurate resource of cell markers for various cell types in tissues of human and mouse. Glutamine synthetase glial fibrillary acidic protein and s100β.

Garden ga and campbell bm 2016 glial biomarkers in human central nervous system disease. In order to differentiate between sgcs and other glial cells researchers have used markers to identify which proteins are found in different cells. Current topics and past controversies. Current topics and past controversies.